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A triplicate of the MD using an apo state of rTs24GTS is shown above (panels A-C), below are the results with rTs24GTS and GSH as substrate (panels D-F)

This would decrease circulating levels of estrogen, gonadotropin-releasing hormone (GnRH), prolactin, and gonadotropins and the ability of melatonin to modulate the activity of enzymes involved in the synthesis of estrogens, both gonadal and extragonadal